Poor circulation can cause cold extremities, numbness, fatigue, and slow wound healing. Supplements that boost nitric oxide production — such as beet root, L-arginine, and nattokinase — help relax blood vessels and improve blood flow throughout the body. Hawthorn berry, garlic, and CoQ10 further support cardiovascular function and healthy circulation.
Quick Comparison
Product
Key Ingredient
Form
Best For
Rating
Lunakai Nattokinase
Nattokinase 400mg (8000 FU)
Capsules
Best Overall
9.5/10
PurePremium Blood Pressure Support
Hawthorn + Hibiscus + Garlic
Capsules
Best Multi-Ingredient
9.4/10
PurePremium Beet Root 14-in-1
Beetroot + Hawthorn + CoQ10
Capsules
Best Beet Root Complex
9.2/10
Snap Supplements Beet Root Powder
Organic Beet Root
Powder
Best Powder
9.1/10
Snap Nitric Oxide L-Arginine
L-Arginine
Capsules
Best Nitric Oxide Booster
9.0/10
Snap Beet Root Gummies
Organic Beet Root + Pomegranate
Gummies
Best Gummies
8.9/10
PurePremium Beet Root 3-in-1
Beets + CoQ10 + Grapeseed
Capsules
Best Simple Formula
8.8/10
1. Lunakai Nattokinase Supplement – Best Overall
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Lunakai USA Made Nattokinase Supplement – 400mg Natto Enzyme, 8000 FU per Serving – Heart & Circulation Support – Non-GMO, 60ct, 4000 FU Capsule
Supports Circulation – Each serving delivers 8000 FU of nattokinase, traditionally sourced to assist in supporting normal blood flow.
Natural Heart Support – Our nattokinase supplement is formulated to complement daily routines focused on overall heart wellness support.
Clean & Simple Ingredients – Each capsule contains 200mg of nattokinase enzyme, delivering 4000 FU, sourced from fermented natto with no artificial flavors or additives.
Vegan-Friendly Formula – Our nattokinase supplement is 100% vegan and plant-based, with no animal-derived ingredients or gelatin.
Made in the USA – Manufactured in the United States in a facility that follows GMP (Good Manufacturing Practices) for quality and consistency.
Nattokinase is one of the most powerful natural enzymes for cardiovascular and circulatory health, and Lunakai delivers a clinical-strength 400mg dose at 8,000 fibrinolytic units per serving.
Derived from the traditional Japanese fermented soybean food natto, nattokinase supports healthy blood flow by promoting the body’s natural fibrinolytic (clot-dissolving) activity. Lunakai’s USA-made formula provides 400mg per serving standardized to 8,000 FU (fibrinolytic units), which is the dosage range used in clinical research. This enzyme works differently from nitric oxide boosters — rather than dilating blood vessels, it helps maintain clean, unobstructed blood flow. The capsules are manufactured in the USA under strict quality standards.
Pros:
Clinical-strength 8,000 FU per serving
Supports healthy blood flow through fibrinolytic activity
USA-made with strict quality manufacturing
Cons:
Not suitable for people on blood-thinning medications
Derived from soy — not appropriate for soy-allergic individuals
Best for: Adults seeking a clinically dosed enzyme supplement for comprehensive circulatory support
2. PurePremium Blood Pressure Support – Best Multi-Ingredient
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PurePremium Blood Pressure Supplements with Hawthorn Berry, Hibiscus, Garlic & Vitamin B12- Nitric Oxide Supplement for Normal Heart Health, Circulation Health & Blood Pressure Support – 90ct
NORMAL BLOOD PRESSURE SUPPORT: Support normal nitric oxide and blood pressure levels already within the normal range with our advanced herbal formula. Crafted from the finest ingredients, it contains potent vitamins for your wellbeing. Take 1 capsule daily of our natural blood pressure support supplement.
NORMAL NITRIC OXIDE SUPPORT: Unlike other nitric oxide supplements for men, PurePremium offers highly absorbable, fast-acting formula. This makes our blood pressure support supplement a perfect nitric oxide supplement for supporting normal cardiovascular health.
ALL IN ONE FORMULA: Experience a blend of nutrients in our blood pressure supplements, featuring, hawthorn berry, hibiscus, garlic extract, olive leaf, buchu leaf, uva ursi, juniper berry, green tea, vitamin C, niacin, vitamin B6, folate, and vitamin B12.
USA-MADE, LAB TESTED: PurePremium Blood Pressure Support supplement is manufactured in a USA-based facility with globally sourced ingredients. Each batch of our nitric oxide supplement is tested by a third-party lab to ensure safety.
CAUTION: CONSULT A HEALTHCARE PROFESSIONAL BEFORE USE: Individuals with pre-existing medical conditions or those taking prescription medications should consult with a healthcare professional before using this supplement. Follow recommended dosage instructions. Seek medical advice for adverse effects.
This comprehensive formula combines hawthorn berry, hibiscus, garlic, and vitamin B12 for multi-pathway circulation and cardiovascular support.
PurePremium’s circulation formula takes a broad approach by combining several clinically studied cardiovascular ingredients. Hawthorn berry supports vasodilation and heart muscle strength, hibiscus helps maintain healthy blood pressure levels, and garlic promotes nitric oxide production for improved blood flow. Added vitamin B12 supports healthy homocysteine levels, which is important for vascular health. The formula works as both a circulation enhancer and blood pressure support supplement.
Pros:
Multi-ingredient approach targets circulation from multiple angles
Hawthorn, hibiscus, and garlic all have strong research backing
Added B12 for homocysteine and vascular health
Cons:
Garlic may cause digestive discomfort in some users
Proprietary blend doesn’t specify individual ingredient amounts
Best for: People who want a broad-spectrum circulation supplement addressing multiple cardiovascular pathways
3. PurePremium Beet Root Capsules 14-in-1 – Best Beet Root Complex
PurePremium Beet Root Capsules for Blood Pressure Support – 14-in-1 Formula with Beetroot Powder, Hawthorn, Hibiscus & Garlic for Normal Nitric Oxide Production & Heart Health – Non-GMO – 90ct
NORMAL BLOOD PRESSURE SUPPORT: Support normal nitric oxide and blood pressure levels already within the normal range with our advanced herbal formula. Crafted from the finest ingredients, it contains potent vitamins for your wellbeing. Take 1 capsule daily of our natural blood pressure support supplement.
NORMAL NITRIC OXIDE SUPPORT: Unlike other nitric oxide supplements for men, PurePremium offers highly absorbable, fast-acting formula. This makes our blood pressure support supplement a perfect nitric oxide supplement for supporting normal cardiovascular health.
ALL IN ONE FORMULA – NOW WITH BEET ROOT: Experience a blend of nutrients in our blood pressure supplements, featuring beetroot, hawthorn berry, hibiscus, garlic extract, olive leaf, buchu leaf, uva ursi, juniper berry, green tea, vitamin C, niacin, vitamin B6, folate, and vitamin B12.
USA-MADE, LAB TESTED: PurePremium Blood Pressure Support supplement is manufactured in a USA-based facility with globally sourced ingredients. Each batch of our nitric oxide supplement is tested by a third-party lab to ensure safety.
CAUTION: CONSULT A HEALTHCARE PROFESSIONAL BEFORE USE: Individuals with pre-existing medical conditions or those taking prescription medications should consult with a healthcare professional before using this supplement. Follow recommended dosage instructions. Seek medical advice for adverse effects.
This 14-in-1 formula amplifies beet root’s nitric oxide benefits with hawthorn berry, CoQ10, and other circulatory support ingredients.
Beet root is one of the most effective natural sources of dietary nitrates, which the body converts to nitric oxide for blood vessel relaxation and improved circulation. PurePremium enhances this effect by combining beetroot powder with 13 additional ingredients including hawthorn berry for heart support, CoQ10 for cellular energy, and grapeseed extract for antioxidant protection. The 14-in-1 formula provides significantly more comprehensive circulatory support than standalone beet root supplements.
Pros:
14 synergistic ingredients beyond basic beet root
Includes CoQ10 and hawthorn for heart health
Targets both nitric oxide production and vascular protection
Cons:
Complex formula may make it harder to identify which ingredients help most
Higher price point than simple beet root supplements
Best for: People who want maximum circulatory benefit from a single supplement combining beet root with complementary ingredients
4. Snap Supplements Organic Beet Root Powder – Best Powder
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Snap Supplements USDA-Certified Organic Beet Root Powder, Nitric Oxide Supplements for Men & Women, Organic Beets & Pomegranate, Supports Healthy Energy Levels, 8.8 oz (1 Month Supply), Mixed Berry
Heart Health & Circulation Support: This plant-based nitric oxide supplement is formulated with organic beetroot to support healthy circulation and heart health, helping you maintain an active lifestyle.*
Clean, Natural Energy Support: Our beetroot supplement helps support healthy energy metabolism—without added sugars or stimulants. Offers a natural, caffeine-free option to support healthy energy levels.*
Antioxidant Support: This nitric oxide powder is enriched with pomegranate and red spinach to support antioxidant protection and cellular health.*
Supports Active Lifestyles: A great choice for adults and fitness enthusiasts who want natural support for daily vitality.* A convenient alternative to beetroot capsules, this beet powder mixes easily into water or smoothies and can be used at home, in the gym, or while traveling.
Quality You Can Trust: Our vitamins and supplements are crafted by health experts and manufactured in the USA with globally sourced ingredients. This supplement is USDA-certified organic, non-GMO, gluten-free, vegan, and manufactured in a GMP-certified facility to ensure purity and potency.
USDA-certified organic beet root powder offers maximum flexibility and absorption for nitric oxide boosting and circulation support.
Powder form delivers faster absorption than capsules and allows flexible dosing. Snap’s USDA-certified organic beet root powder provides clean, concentrated beet root nutrition without fillers or additives. The organic certification ensures the beets are grown without synthetic pesticides or fertilizers. Beet root powder can be mixed into smoothies, water, or juice for easy daily consumption. This format delivers higher nitrate content per serving than most capsule products.
Pros:
USDA Organic certification for clean sourcing
Powder form allows flexible dosing and fast absorption
Higher nitrate content per serving than capsules
Cons:
Earthy beet flavor may not appeal to everyone
Less convenient than capsules for on-the-go use
Best for: People who prefer powder supplements and want maximum nitrate delivery for circulation support
5. Snap Supplements Nitric Oxide with L-Arginine – Best Nitric Oxide Booster
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Snap Supplements Nitric Oxide Supplement with L-Arginine to Support Energy, Quick Recovery, Heart Health, Muscle Growth & Circulation, 90 Vegetarian Capsules
Supports Oxygen Delivery & Natural Energy – Nitric Oxide plays a role in circulation and energy production, supporting healthy circulation and daily vitality. Our Nitric Oxide Booster supports natural nitric oxide levels and features ginseng root, traditionally used to promote stamina, endurance, and sustained energy—without stimulants or added sugars.
Promotes Healthy Circulation & Cardiovascular Wellness – By supporting healthy blood flow throughout the body, our nitric oxide supplement promotes natural circulation and helps maintain heart and overall circulatory wellness. This blend helps you stay active and feel good, naturally.
L-Arginine & L-Citrulline For Active Energy & Performance – Formulated with three forms of L-Arginine and L-Citrulline, key amino acids that help support the body’s natural nitric oxide production, this supplement promotes energy production, supports healthy immune function, and helps maintain muscle health and recovery. Because natural production may vary, supplementing with L-Arginine can help support circulation, stamina, workout endurance, and overall wellness for an active lifestyle.
Enhance Your Wellness Routine: Ideal for fitness enthusiasts and active adults who want to support natural energy, workout recovery, and healthy circulation. Best used alongside a balanced diet, regular exercise, and your favorite gym supplements. Convenient for use at home, in the gym, or on the go.
Quality You Can Trust: Our vitamins and supplements are crafted by health experts and manufactured in the USA with globally sourced ingredients. This supplement is non-GMO, free of major allergens, gluten-free, and manufactured in a GMP-certified facility to ensure purity, potency, and quality. It contains no gelatin, dairy, or other animal-derived substances – making it a great option for vegans & vegetarians.
L-Arginine is the direct precursor to nitric oxide production, and Snap’s formula delivers it alongside supporting ingredients for energy and quick recovery.
While beet root provides dietary nitrates, L-arginine takes a different pathway — it serves as the direct substrate for nitric oxide synthase, the enzyme that produces nitric oxide in blood vessel walls. Snap’s formula pairs L-arginine with complementary ingredients to support energy levels, exercise recovery, and overall circulation. The vegetarian capsules are manufactured in the USA and are free from major allergens. This formula is popular with both men and women seeking improved blood flow.
Pros:
Direct nitric oxide precursor for rapid vasodilation
Supports both circulation and exercise performance
Clean, allergen-free vegetarian formula
Cons:
L-arginine may be less effective in older adults (L-citrulline may be better)
Multiple capsules per serving
Best for: Active adults who want to boost nitric oxide production for improved blood flow and exercise performance
6. Snap Supplements Nitric Oxide Beet Root Gummies – Best Gummies
Snap Supplements Nitric Oxide Beet Root Gummies – Beet Root Supplement with Pomegranate Powder Supports Healthy Circulation & Natural Energy, 60 Sugar-Free Gummies (1 Month Supply), Cherry
Plant-Based Beets Supplement: Made with 300 mg beet root extract (4:1) and pomegranate powder, these nitric oxide gummies help support healthy circulation—offering a simple way to enhance your wellness regimen.*
Antioxidant Blend for Cellular Support: A 14 mg antioxidant blend featuring green tea, tart cherry, turmeric, green coffee bean, kale, blueberry, and broccoli helps provide antioxidant support for cellular well-being throughout the day.*
Easy Daily Support for Busy, Active Lifestyles: A convenient alternative to beet root powder or beet root capsules, this nitric oxide supplement supports natural energy and general wellness—ideal at home, at work, or on the go.*
Vegan, Non-GMO Gummies for Men & Women: This vegan, non-GMO, gluten-free beetroot supplement is manufactured in a GMP-certified facility to ensure purity and potency. A simple way to support overall wellness, our beets supplements fit seamlessly into active, health-focused lifestyles.*
Clean, Great-Tasting Nitric Oxide Support Formula: Manufactured in the USA with globally sourced ingredients, these beets gummies fit effortlessly into daily wellness habits—offering a great-tasting way to support healthy nitric oxide levels already within normal range.*
These beet root gummies combine organic beets with pomegranate powder for a delicious, chewable nitric oxide boost.
For people who prefer gummies over capsules or powders, Snap’s beet root gummies deliver circulation support in a convenient, great-tasting format. The formula pairs organic beet root extract with pomegranate powder — another potent source of nitric oxide-boosting polyphenols. Pomegranate has been shown in studies to improve blood flow and protect blood vessel lining. The gummy format ensures easy daily compliance without water or mixing.
Pros:
Enjoyable gummy format for easy daily use
Combines beet root with pomegranate for dual nitric oxide support
No water needed — convenient for travel and on-the-go use
Cons:
Lower concentration per serving than capsules or powder
Contains added sugars inherent to gummy format
Best for: People who want a convenient, tasty way to support circulation without swallowing capsules
7. PurePremium Beet Root Capsules 3-in-1 – Best Simple Formula
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PurePremium Beet Root Capsules – 3-in-1 Blood Pressure Supplements with Beets, CoQ10 & Grapeseed – Beetroot Capsules Nitric Oxide Supplement for Normal Heart Health & Circulation Health – 60ct
3-IN-1 BLOOD PRESSURE SUPPORT FORMULA: Our beets supplements combine the power of Beetroot, CoQ10, and Grape Seed Extract to help support blood pressure levels already within the normal range and normal cardiovascular wellness.*
HEALTHY CIRCULATION & NITRIC OXIDE SUPPORT: Beet root supplements naturally support nitric oxide production, normal circulation, and nutrient delivery throughout the body—helping you feel energized and balanced every day.*
NORMAL HEART HEALTH SUPPLEMENTS: Formulated with CoQ10, a compound essential for normal energy production in heart cells, this supplement supports cardiovascular vitality and helps maintain healthy heart function as part of your daily routine.*
GRAPE SEED FOR ANTIOXIDANT & VASCULAR SUPPORT: Grape Seed Extract provides natural antioxidants that help protect against oxidative stress and support the integrity of healthy blood vessels—supporting normal circulation and heart function.*
PUREPREMIUM QUALITY YOU CAN TRUST: Made in the USA from globally sourced ingredients under strict GMP standards. 3rd-party lab-tested, Non-GMO, plant-based, and free from gluten, soy, dairy, and artificial sweeteners—for purity and potency.*
A streamlined formula combining beets, CoQ10, and grapeseed extract for focused circulatory support without overwhelming ingredient lists.
This 3-in-1 approach keeps things simple by combining three proven circulatory ingredients: beet root for nitric oxide production, CoQ10 for cellular energy and heart support, and grapeseed extract for powerful antioxidant protection of blood vessels. Grapeseed extract contains oligomeric proanthocyanidins (OPCs) that help strengthen capillary walls and reduce oxidative damage to the cardiovascular system. The focused formula makes it easy to understand exactly what each ingredient contributes.
Pros:
Clean 3-ingredient formula with clear purpose for each component
CoQ10 supports heart energy alongside circulation
Grapeseed OPCs protect blood vessel integrity
Cons:
Fewer ingredients than the 14-in-1 version
No vasodilating herbs like hawthorn or hibiscus
Best for: People who prefer a simple, transparent formula with just three proven circulation ingredients
8. Snap Supplements Beet Root Nitric Oxide Gummies – Best Organic Gummies
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Snap Supplements Nitric Oxide Beet Root Gummies Supplement with Organic Beets – Energy & Circulation Support, 60 Sugar-Free Gummies (30 Servings, 1 Month Supply), Peach
Energy & Circulation Support: Powered by beet root and pomegranate juice powder—supports healthy blood flow and circulation to help maintain natural, steady energy throughout your day.
Nitric Oxide Production: Formulated to help maintain nitric oxide levels that support vascular health, endurance, and vitality.
Designed for Active Lifestyles: Created for men and women who want to stay active—perfect for workouts, travel, or busy workdays when balanced energy and stamina matter most.
Convenient and Great-Tasting: Use as your daily gummy supplement—no mixing or water required. Take them at home, the office, or the gym as part of your wellness routine.
Quality You Can Trust: This plant-based supplement is designed for people interested in clean nutrition—manufactured in the USA with globally sourced ingredients, vegan, non-GMO, gluten-free and produced in a GMP-certified facility for purity and potency.
Snap’s organic beet root gummy formula supports energy and circulation with a clean, organic ingredient profile.
These gummies feature organic beet root extract as their foundation, designed specifically for energy and circulation support. The organic certification ensures premium sourcing standards while the gummy format makes daily supplementation effortless. Each serving delivers meaningful beet root extract to support the body’s natural nitric oxide production. This is a solid option for people who want organic quality in a convenient gummy format.
Pros:
Organic beet root for clean, premium quality
Convenient gummy format for daily compliance
Supports both energy and circulation
Cons:
Gummies deliver less concentrated beet root than capsules
Added ingredients for flavor and texture
Best for: People who prioritize organic quality and prefer gummies for their daily circulation supplement
How to Choose the Best Circulation Supplement
The most effective circulation supplements work through nitric oxide pathways. Beet root provides dietary nitrates that convert to nitric oxide, while L-arginine and L-citrulline serve as direct precursors. Nattokinase supports blood flow through fibrinolytic activity. Hawthorn berry, garlic, and hibiscus offer additional vasodilatory benefits. Choose a product that targets at least one of these primary mechanisms.
Dosage varies by ingredient. Beet root supplements typically range from 500-1,500mg per serving; look for products listing nitrate content for precise dosing. L-arginine is most effective at 2-6g daily, while nattokinase should provide at least 2,000 FU per serving (clinical studies often use 4,000-8,000 FU). Hawthorn berry extract is typically dosed at 160-900mg daily.
Circulation supplements come in capsules, powders, and gummies. Capsules offer the best concentration and convenience, powders provide the fastest absorption and highest doses, and gummies offer the easiest compliance for daily use. Powder beet root delivers more nitrates per serving than capsules but requires mixing. Choose based on your lifestyle and preferences.
Look for GMP-certified manufacturing, third-party testing, and organic certifications where available. People taking blood thinners should avoid nattokinase and high-dose garlic without medical supervision. Those on blood pressure medication should consult a doctor before adding nitric oxide boosters, as the combined effect could lower blood pressure excessively.
Frequently Asked Questions
What supplements help improve circulation?
The most effective circulation supplements include beet root (rich in nitrates that convert to nitric oxide), nattokinase (an enzyme that supports healthy blood flow), L-arginine and L-citrulline (direct nitric oxide precursors), hawthorn berry (supports vasodilation), garlic (promotes nitric oxide and thins blood), and grapeseed extract (strengthens blood vessel walls). Many people benefit from combining multiple approaches.
How much beet root should I take daily for circulation?
Most beet root supplements provide 500-1,500mg per serving. For circulation benefits, aim for the higher end of this range, or choose a product that specifies nitrate content (200-400mg of dietary nitrates daily is the typical research range). Powder forms generally deliver more nitrates per serving. Beet juice concentrate is another option, with most studies using 70-140ml of concentrated beet juice.
When is the best time to take circulation supplements?
Circulation supplements work best when taken in the morning with food, allowing peak nitric oxide levels during active daytime hours. Beet root and L-arginine can be taken 1-2 hours before exercise for enhanced blood flow during activity. Nattokinase is commonly taken on an empty stomach for optimal enzyme activity. Consistency matters most — take your supplement at the same time daily.
Are circulation supplements safe with blood pressure medications?
Circulation supplements that boost nitric oxide can lower blood pressure, which may compound the effects of blood pressure medication. This is especially true for beet root, L-arginine, and garlic. Nattokinase should not be combined with blood-thinning medications like warfarin. Always inform your doctor about any supplements you take, particularly if you’re on cardiovascular medications.
Can I take multiple circulation supplements together?
Combining complementary circulation supplements can be effective. For example, beet root (dietary nitrate pathway) and L-arginine (L-arginine-NO pathway) work through different mechanisms and can be safely stacked. Adding CoQ10 or hawthorn berry provides additional cardiovascular support. However, avoid combining nattokinase with other blood-thinning supplements like fish oil or garlic without medical guidance.
How long does it take for circulation supplements to work?
Acute effects from beet root and L-arginine can be felt within 1-3 hours, with blood flow improvements measurable within a single dose. However, sustained circulation benefits build over 2-4 weeks of consistent daily use. Nattokinase typically requires 4-8 weeks for full fibrinolytic benefits. Hawthorn berry may take 6-12 weeks to achieve peak cardiovascular effects.