DHT (dihydrotestosterone) is a hormone derived from testosterone that plays a major role in pattern hair loss. When DHT binds to receptors in hair follicles, it causes them to shrink and eventually stop producing new hair. DHT blocker supplements use natural ingredients like saw palmetto, pumpkin seed oil, and biotin to inhibit 5-alpha-reductase — the enzyme responsible for converting testosterone into DHT — helping to slow hair loss and support healthier hair growth.
Quick Comparison
Product
Key Ingredient
Form
Best For
Rating
Lunakai Super Hair Gummies
Saw Palmetto + Biotin
Gummies
Best Overall
9.5/10
PurePremium Saw Palmetto
Saw Palmetto 500mg
Capsules
Best Saw Palmetto
9.4/10
Snap Supplements Prostate Health
Saw Palmetto + DHT Blocker Blend
Capsules
Best for Men
9.3/10
Zazzee Saw Palmetto 20:1
Saw Palmetto Extract 6000mg
Capsules
Most Potent
9.2/10
Advanced Trichology DHT Blocker
Multi-Ingredient DHT Complex
Capsules
Best Clinical Formula
9.1/10
Lustriva DHT Blocker
Lustriva Blend
Capsules
Best for Women
9.0/10
Propidren by HairGenics
Saw Palmetto + Biotin
Capsules
Best Value
8.9/10
1. Lunakai Super Hair Gummies – Best Overall
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Lunakai USA Made Super Hair Gummies with Biotin, Zinc, Horsetail Extract & Saw Palmetto – Hair Growth Vitamins for Women & Men – Supports Thicker, Longer, Stronger Tresses, Skin & Nails, 60ct
Hair Growth Support – These hair growth vitamins are designed to help support thicker, longer-looking hair by providing nutrients your body needs to thrive.
Gummy Convenience – Our hair gummies for women and men are a delicious, chewable alternative to pills—easy to take daily, no water or swallowing required.
Biotin + Vitamin E – Featuring biotin for hair growth support and vitamin E for hair, this blend helps nourish from within for hair, skin, and nails support.
Vegan & Gelatin-Free – These vegan hair growth gummies are made without gelatin or animal products—perfect for plant-based lifestyles and dietary sensitivities.
No Artificial Flavors – Enjoy natural-tasting hair vitamins gummies with no artificial flavors, colors, or sweeteners—just clean ingredients you can trust.
A tasty, well-rounded hair support gummy that combines DHT-blocking saw palmetto with growth-promoting biotin, zinc, and horsetail extract in one convenient daily dose.
Each serving delivers saw palmetto extract alongside 5,000 mcg of biotin, zinc, and horsetail extract — all key nutrients for combating DHT-related thinning. The gummy format makes it easy to stay consistent without swallowing large capsules. Manufactured in the USA in a GMP-certified facility with no artificial colors or preservatives.
Pros:
Combines DHT blocking with hair growth support in one supplement
Pleasant-tasting gummy format improves compliance
Includes biotin, zinc, and horsetail for comprehensive hair nutrition
Cons:
Lower saw palmetto dose compared to standalone capsule options
Contains added sugars typical of gummy supplements
Best for: Anyone who wants DHT support and hair growth nutrients in one easy-to-take gummy
2. PurePremium Saw Palmetto 500mg – Best Saw Palmetto
PurePremium Saw Palmetto 500 mg for Men/Women – Maximum Strength Saw Palmetto Extract | Powder Capsules Supplement – Support Normal Urinary Tract, Prostate Health/Hair – 3 Months Supply – 100 Tablets
Presenting The Maximum Strength PurePremium Saw Palmetto Supplement – Our capsules include highly potent Saw Palmetto powder extract (500mg per capsules) that is enhanced by a saw palmetto berries powder complex for maximum strength and absorption.
Saw Palmetto for Mens Normal Prostate Health – saw palmetto prostate supplement to support normal prostate and urinary tract health for men!
All Natural Saw Palmetto for Women – Not just a prostate supplement for men but may also promote normal hair growth for both men and women. The Saw Palmetto berry extract has normal hormone-balancing benefits.
For Maximum Benefits – enjoy a healthy and effective way to support your normal urinary tract and prostate health with our easy-to-swallow capsules. Enhanced formula with high potency and bio-availability for better absorption.
Premium Quality, Go PurePremium – a stamp of quality you can trust. All of our supplements are formulated in the USA. Made with a natural and potent formula of saw palmetto 500mg extract with a powerful berry powder complex. Take 1 a day!
A straightforward, high-dose saw palmetto capsule that delivers one of the most well-researched natural DHT blockers at a clinically relevant dosage.
Each capsule provides 500 mg of maximum-strength saw palmetto extract, the gold-standard natural 5-alpha-reductase inhibitor. The powder capsule format ensures rapid absorption. Free from gluten, soy, dairy, and artificial additives. Suitable for both men and women looking to address hormonal hair loss naturally.
Pros:
Clinically relevant 500 mg dose of pure saw palmetto
Clean formula with no unnecessary fillers
Works for both men and women
Cons:
Single-ingredient formula lacks complementary hair nutrients
Results may take 2-3 months to become noticeable
Best for: Those who want a focused, single-ingredient saw palmetto DHT blocker
3. Snap Supplements Prostate Health with DHT Blocker – Best for Men
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Snap Supplements Prostate Health Supplement with Saw Palmetto for Men, DHT Blocker – Helps Support Male Urinary Tract and Prostate for Mens Health, 90 Vegetarian Capsules (30 Servings, 1 Month Supply)
Supports Healthy Prostate & Urinary Function: Our prostate health supplement for men is formulated with saw palmetto, stinging nettle root extract, and beta-sitosterol to help maintain healthy prostate function, promote urinary comfort, and support bladder tone for fewer nighttime bathroom trips.*
Turmeric For Inflammatory Balance: Our prostate support supplement features turmeric extract standardized to 95% curcuminoids, along with magnesium. Together, these ingredients support a healthy inflammatory response and overall cellular wellness.*
Prostate Health Mushroom Blend: Combines maitake and reishi mushrooms with supportive botanicals and nutrients to deliver antioxidant cellular protection. Helps maintain healthy immune function and supports the body’s natural detoxification pathways while promoting overall prostate wellness.*
DHT Blocker for Men: Features plant-based ingredients traditionally used to support men’s overall wellness and promote healthy hair and scalp. Designed for those seeking natural, botanical support, this formula pairs easily with daily vitamins for men and is convenient to take with food at home or on the go.*
Quality You Can Trust: Our vitamins and supplements are crafted by health experts and manufactured in the USA with globally sourced ingredients. This supplement is non-GMO, free of major allergens, gluten-free, vegan, and manufactured in a GMP-certified facility to ensure purity, potency, and quality.
A dual-purpose formula designed for men that blocks DHT while simultaneously supporting prostate health — two concerns that share a common hormonal pathway.
This supplement combines saw palmetto with a proprietary DHT blocker blend that includes pumpkin seed extract, pygeum bark, and stinging nettle — all traditional prostate and hair support botanicals. The multi-ingredient approach targets DHT through several mechanisms rather than relying on a single pathway. Made in the USA in a GMP-certified facility.
Pros:
Addresses both hair loss and prostate health in one formula
Multi-ingredient DHT blocking approach
Includes pygeum and stinging nettle for additional 5-AR inhibition
Cons:
Proprietary blend doesn’t disclose individual ingredient amounts
Primarily marketed toward men
Best for: Men experiencing hair thinning who also want prostate health support
4. Zazzee Extra Strength Saw Palmetto 20:1 Extract – Most Potent
Zazzee Extra Strength Saw Palmetto 20:1 Extract, 6000 mg Strength, 40% Fatty Acids, 120 Vegan Capsules, 4 Month Supply, Concentrated and Standardized 20X Extract, Non-GMO, All-Natural, Made in the USA
OUTSTANDING VALUE / 4 MONTH SUPPLY: Our Extra Strength Saw Palmetto Extract contains 6000 mg strength per capsule AND 120 capsules per bottle – an amazing value! A single bottle contains a 4 month supply. Compare this to other leading brands that require 2 capsules per serving, contain less than 120 capsules, and use a much less potent, non-extract powder. Our Extra Strength Saw Palmetto Extract is a bargain not be found elsewhere!
6000 MG STRENGTH / POTENT 20:1 EXTRACT: Each capsule contains 6000 mg strength of Saw Palmetto Extract from a potent, powerful 20:1 extract. Combine that with a minimum of 40% Fatty Acids, and our Extra Strength Saw Palmetto Extract, commonly used for prostate and urinary tract health, is one of the strongest dosages available!
40% FATTY ACIDS: Fatty Acids are the “good stuff”, the beneficial compound in Saw Palmetto that provides the desired results. Our Saw Palmetto Extract has been standardized to contain a minimum of 40% Fatty Acids, which is one of the highest standardization numbers available. The higher the numbers, the more potent the extract. Clearly, not all Saw Palmetto is created equal!
NATURAL, VEGAN, & NON-GMO: All ingredients, including the capsule, are 100% vegan. Our Extra Strength Saw Palmetto Extract does not contain any sweeteners, artificial flavors, wheat, corn, gluten, soy, milk, egg, fish, shellfish, or tree nut ingredients. Enjoy the amazing benefits of our potent Saw Palmetto Extract without worrying about what else might be hiding in each capsule!
GOLD STANDARD PRODUCTION: Your health and safety mean everything to us. For that reason, our Extra Strength Saw Palmetto Extract is manufactured in the USA, in a fully certified facility with adherence to good manufacturing policies and under the most stringent quality control. You can rest assured that you get the best value for your money!
With a concentrated 20:1 extract delivering 6,000 mg equivalent strength and 40% fatty acids, this is one of the most potent saw palmetto DHT blockers available on Amazon.
The 20:1 extraction ratio concentrates the active compounds — particularly the fatty acids and sterols responsible for inhibiting 5-alpha-reductase. Each bottle contains 120 vegan capsules for a 4-month supply, making it excellent value. Standardized to 40% fatty acids, which is higher than most competitors. Third-party tested for purity and potency.
Pros:
6,000 mg equivalent strength per capsule from 20:1 extract
Standardized to 40% fatty acids for consistent potency
4-month supply per bottle at competitive price
Cons:
High potency may not be necessary for everyone
Extract-only formula without additional hair support nutrients
Best for: Users who want the highest-potency saw palmetto extract for aggressive DHT blocking
5. Saw Palmetto for Women with Biotin – Best DHT Blocker for Women
Saw Palmetto for Women with 2500mcg Biotin – DHT Blocker and Hair, Skin, Nail Health Gummies – 60 Count – Supports Stronger and Fuller Looking Locks and Radiant Skin – Vegan, Non-GMO, 1 Month Supply
Raspberry-Flavored Convenience – Enjoy the delicious taste of raspberry in a gummy form, making it easier to incorporate prostate health support into your daily regimen while enjoying a flavorful treat.
Prostate Health & Urinary Function – Designed to support men’s health, our gummies help support a healthy prostate and urinary tract, offering a comprehensive approach to male wellness.
Daily DHT Blocker Supplement – Take control of your hair health with a daily serving of these saw palmetto gummies, crafted to help block DHT, a hormone linked to hair and prostate health in men.
Vegan & Herbal Formula – Our gummies feature saw palmetto extract, a widely recognized herbal ingredient that supports hormone balance and hair health, all in a convenient, vegan-friendly gummy form.
man gummy woman prostate support supplement health dht blocker
Specifically formulated for women experiencing DHT-related hair thinning, this supplement pairs saw palmetto with 2,500 mcg of biotin plus hair, skin, and nail supporting nutrients.
Women can experience DHT-related hair loss too, particularly during hormonal transitions like menopause. This formula addresses that with saw palmetto for DHT inhibition alongside biotin, collagen-supporting vitamins, and other nutrients tailored for women’s hair health. The combination targets both the hormonal cause and provides building blocks for stronger, thicker hair regrowth.
Pros:
Formulated specifically for women’s hormonal hair loss
Combines DHT blocking with 2,500 mcg biotin
Supports hair, skin, and nail health simultaneously
Cons:
Lower saw palmetto dose than men’s formulas
May not be potent enough for severe hair loss
Best for: Women experiencing hormonal hair thinning who want a gentle, multi-benefit formula
6. Advanced Trichology DHT Blocker with Immune Support – Best Clinical Formula
DHT Blocker – Hair Growth Supplement for Genetic Thinning for Men and Women | Approved* by American Hair Loss Association | Guaranteed, Backed by 20 Years of Experience in Hair Loss Treatment Clinics
The trusted and approved* DHT Blocker hair growth supplement for women. andmen. Ideal for hair loss and thinning hair on the top of your head, crown, or frontal hairline. Target hair loss caused by genetics and pattern hair loss with a powerful formula with 11 natural ingredients for optimal health, hair loss control, and immune system support.
Gluten-free vegetarian clinically developed DHT Blocker for thinning hair. Our formula is completely unique and developed for those losing hair due to DHT, hormonal changes, stress, and digestive problems. Only DHT Blocker with powerful DHT blocking herbs, probiotics, and prebiotics.
American Hair Loss Association Approved. First and Only DHT Blocker Supplement Approved* Ever. Backed by 20 Years of in-clinic hair loss treatment experience. Advanced Trichology has owned and operated hair loss treatment clinics across the United States for 20 years.
Grow thicker fuller hair, and control hair loss. Our hair loss supplements have been scientifically tested in our clinics on thousands of male and female hair loss clients with Amazing Success. #1 Top Product for DHT Blockers by Trichology dot com 2021.
Developed by certified trichologists with 20+ years of clinical hair loss treatment experience, this is the only DHT blocker supplement approved by the American Hair Loss Association.
This formula goes beyond simple DHT blocking with a comprehensive approach that includes saw palmetto, green tea extract (EGCG), pygeum bark, zinc, stinging nettle, L-lysine, and probiotics. The inclusion of gut health support addresses nutrient absorption issues that can compound hair loss. Backed by in-clinic use on thousands of patients and formulated by William Gaunitz, a board-certified trichologist.
Pros:
Only DHT blocker approved by the American Hair Loss Association
11 clinically selected ingredients targeting multiple hair loss pathways
Includes probiotics for improved nutrient absorption
Cons:
Premium price point compared to basic saw palmetto supplements
Requires consistent daily use for 3-6 months to see results
Best for: Anyone who wants a clinically developed, multi-pathway DHT blocking formula
7. Lustriva Hair Growth Supplement – Best Multi-Ingredient DHT Blocker
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A comprehensive hair growth formula that combines the patented Lustriva blend with DHT-blocking botanicals for women experiencing thinning and shedding.
The Lustriva complex delivers a targeted combination of ingredients designed to block DHT production, reduce hair shedding, and support the growth of thicker, fuller hair. The formula includes saw palmetto alongside vitamins and minerals that support the hair growth cycle from multiple angles. Each bottle provides a full month’s supply in easy-to-swallow capsules.
Pros:
Patented Lustriva blend backed by ingredient research
Targets DHT blocking plus hair growth stimulation
Well-suited for female pattern thinning
Cons:
Proprietary blend makes it hard to evaluate individual dosages
Results vary significantly between users
Best for: Women looking for a comprehensive DHT blocker with additional hair growth support
8. DIM Supplement for Men 300mg – Best Hormonal Balance DHT Support
DIM Supplement for Men 300mg | Estrogen Blocker & Aromatase Inhibitor | Extra Strength Men’s Hormone Balance & Fitness Booster with Diindolylmethane Plus CDG & Broccoli Floret | Gluten-Free | 60 Ct
ESTROGEN BLOCKER FOR MEN: Diindolylmethane (DIM) works as an estrogen blocker by promoting the metabolism of estrogen into less potent forms and inhibiting the activity of enzymes that convert androgens to estrogen.*
MEN’S HEALTH & HORMONE BALANCE: By supporting men’s breakdown of excess estrogen, this DIM supplement for men supports healthy male hormone levels, fitness, prostate health, energy, and more.*
EXTRA STRENGTH DIM: Every once-daily capsule of DIM for men contains DIM 300mg, and each bottle contains a convenient 2-month supply. BioPerine is also included to help make this complex highly absorbable.
WITH CALCIUM D-GLUCARATE (CDG): Our DIM formula for men includes CDG for its ability to further support estrogen breakdown, liver detox and hormone balance.* DIM 300mg for Men provides DIM plus CDG in one easy-to-use supplement.*
THE SMNUTRITION DIFFERENCE: DIM 300 for Men is Third-Party Tested, and Certified Gluten-Free. It is formulated Non-GMO, Vegan, Silicon Dioxide Free, and Magnesium Stearate-Free, and is manufactured in a facility that is certified GMP-compliant.
DIM (diindolylmethane) takes a different approach to DHT management by supporting healthy estrogen metabolism and overall hormonal balance, which indirectly influences DHT levels.
This 300 mg DIM formula works as an aromatase inhibitor and estrogen blocker, helping to optimize the testosterone-to-DHT conversion pathway. While not a direct 5-alpha-reductase inhibitor like saw palmetto, DIM supports the broader hormonal environment that influences DHT production. Each capsule includes BioPerine for enhanced absorption. 60 capsules per bottle for a 2-month supply.
Pros:
Addresses hormonal balance beyond just DHT
300 mg dose with BioPerine for enhanced bioavailability
Supports estrogen metabolism alongside DHT management
Cons:
Indirect DHT support rather than direct 5-alpha-reductase inhibition
Better suited as part of a stack rather than a standalone solution
Best for: Men who want to address hormonal imbalance contributing to both DHT and estrogen issues
9. Saw Palmetto Prostate Supplement 500mg – Best Budget Pick
Saw Palmetto for Men Prostate Health Supplement to Promote Urinary Tract Function – 500mg Per Serving – 100 Count – DHT Blocker Hair Vitamin – Vegan, Non-GMO Capsules, Over 3 Month Supply
Prostate Supplements for Men – Our leading Saw Palmetto capsules feature the finest complex of saw palmetto extract to help support prostate health for men, decrease BPH levels, and reduce urinary frequency as you age.
Daily Convenience for Prostate Health – Prioritize your prostate health effortlessly with just one saw palmetto capsule a day. For added nighttime support, pair it with our evening formula to help reduce urination frequency at night.
Saw Palmetto Extract – Our daily capsules are formulated with nutrient-rich saw palmetto berries, known for their prostate health and hormone balance benefits, promoting overall wellness and vitality in aging men.
Look and Feel Younger – Not only does our Saw Palmetto supplement aid in prostate health, but it also acts as a DHT blocker, supporting hair health, which helps you feel more confident and youthful.
Prostate Health Supplements for Men – Feel confident and regain your alpha male status with saw palmetto. Support your health and well-being with our daily vegan, non-GMO capsules.
A no-frills, affordable saw palmetto supplement that delivers 500 mg per serving for basic DHT blocking and prostate support without the premium price tag.
This straightforward formula provides 500 mg of saw palmetto extract designed to promote urinary tract function and support healthy DHT levels. The simple ingredient list keeps the price accessible for users who want to try saw palmetto without committing to a premium multi-ingredient formula. GMP-manufactured with clean, vegetarian-friendly capsules.
Pros:
Budget-friendly price for a full-dose saw palmetto
Clean, simple formula with minimal additives
Good entry point for those new to DHT blockers
Cons:
Basic formula lacks biotin, zinc, or other hair support nutrients
Not standardized for specific fatty acid content
Best for: Budget-conscious buyers who want a simple, effective saw palmetto supplement
How to Choose the Best DHT Blocker Supplement
The most effective DHT blockers contain saw palmetto extract, which is the most well-researched natural 5-alpha-reductase inhibitor. Look for products standardized to contain a minimum percentage of fatty acids (ideally 40% or higher), as these are the active compounds responsible for DHT inhibition. A dosage of 320–500 mg of saw palmetto extract per day is consistent with the amounts used in clinical studies.
Consider whether you want a single-ingredient saw palmetto supplement or a multi-ingredient formula. Single-ingredient options offer more control over dosage and are easier to combine with other supplements. Multi-ingredient formulas often add biotin, zinc, pumpkin seed oil, pygeum bark, and stinging nettle for a more comprehensive approach to hair loss from multiple angles.
Capsules and softgels are the most common forms and tend to offer higher doses than gummies. However, gummy formats can improve compliance for those who struggle with pills. Whichever form you choose, look for GMP-certified manufacturing, third-party testing, and clean ingredient lists free from unnecessary fillers and artificial additives.
Patience is critical with DHT blockers. Hair growth cycles are long, and most users need 3–6 months of consistent daily use before noticing meaningful improvements in hair thickness and reduced shedding. Combining a DHT blocker with a topical treatment like minoxidil can enhance results for those with more advanced thinning.
Frequently Asked Questions
What is DHT and why does it cause hair loss?
DHT (dihydrotestosterone) is a hormone derived from testosterone via the enzyme 5-alpha-reductase. In people genetically predisposed to pattern hair loss, DHT binds to receptors in hair follicles, causing them to shrink (miniaturize) over time. This leads to progressively thinner hair until the follicle stops producing visible hair entirely. DHT blockers work by inhibiting 5-alpha-reductase or preventing DHT from binding to follicle receptors.
How much saw palmetto should I take daily for DHT blocking?
Most clinical studies use 320–500 mg of saw palmetto extract per day. Higher-potency extracts (such as 20:1 concentrates) deliver equivalent strength from smaller doses. Consistency matters more than megadosing — taking the recommended amount daily for several months yields better results than intermittent high doses.
When is the best time to take a DHT blocker supplement?
Most DHT blockers can be taken at any time of day, though taking them with a meal that contains some fat can improve absorption of the fat-soluble compounds in saw palmetto. Some users prefer morning dosing for consistency, while others take them at night. The key is picking a time you can stick with daily.
Are there any side effects of DHT blocker supplements?
Natural DHT blockers like saw palmetto are generally well-tolerated. Some users report mild digestive discomfort, headaches, or nausea, especially when starting. Because DHT plays a role in hormonal balance, some men may experience changes in libido, though this is uncommon at supplement dosages. Pregnant or nursing women should avoid saw palmetto supplements.
Can women take DHT blocker supplements?
Yes, women can experience DHT-related hair thinning, particularly during perimenopause and menopause when hormonal shifts occur. Several supplements are formulated specifically for women’s DHT-related hair loss. However, women who are pregnant, breastfeeding, or taking hormonal medications should consult a healthcare provider before using any DHT blocker.
How long does it take for DHT blockers to work?
Most users begin noticing reduced shedding within 4–8 weeks and visible improvements in hair thickness within 3–6 months. Hair growth cycles are inherently slow, and follicles need time to recover from DHT damage. Full results typically become apparent after 6–12 months of consistent daily use. Stopping supplementation usually leads to gradual return of hair loss.