Vitamin C and zinc are two of the most studied nutrients for immune support, and combining them in a single supplement makes daily immune defense simple. Vitamin C is a powerful antioxidant that supports white blood cell production, while zinc is essential for immune cell development and inflammatory response. Together, they provide a research-backed foundation for year-round immune health.
Quick Comparison
Product
Key Ingredient
Form
Best For
Rating
Zazzee Advanced Immune Support
Vitamin C 1000mg + Zinc 30mg
Tablets
Best Overall
4.6/5
Zazzee 8-in-1 Immune Support
Vitamin C 1000mg + Zinc + 6 More
Capsules
Best Multi-Ingredient
4.6/5
Snap Supplements Men’s Multivitamin
Vitamin C + Zinc + D3 + Multi
Capsules
Best Multivitamin with C & Zinc
4.5/5
Elderberry Gummies with Vitamin C & Zinc
Elderberry + Vitamin C + Zinc
Gummies
Best Gummies
4.5/5
Natures Craft Kids Immune Gummies
Vitamin D + Vitamin C + Zinc
Gummies
Best for Kids
4.5/5
Elderberry Capsules with Zinc & Vitamin C
Elderberry + Vitamin C + Zinc
Capsules
Best Capsule Combo
4.5/5
BioSchwartz Elderberry + Zinc + Vitamin C
Elderberry + Vitamin C + Zinc
Gummies
Best Premium Gummies
4.4/5
1. Zazzee Advanced Immune Support – Best Overall
No products found.
Zazzee delivers 1000mg of vitamin C paired with 30mg of zinc in a single vegan tablet, offering one of the cleanest and most potent vitamin C + zinc formulas on the market.
Each tablet provides a full 1000mg of vitamin C alongside 30mg of zinc for comprehensive daily immune support. The formula is vegan, non-GMO, and made in a GMP-certified facility. A single bottle provides a 30-day supply with just one tablet per day, making it one of the simplest immune support routines available.
Pros:
High-dose 1000mg vitamin C + 30mg zinc per tablet
One tablet per day — simple daily routine
Vegan and non-GMO with clean ingredients
Cons:
Tablet form may be large for some people to swallow
No additional immune ingredients beyond C and zinc
Best for: Anyone who wants a straightforward, high-potency vitamin C and zinc supplement with clean ingredients
2. Zazzee Extra Strength 8-in-1 Immune Support – Best Multi-Ingredient
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This 8-in-1 formula combines 1000mg vitamin C and zinc with elderberry, echinacea, garlic, turmeric, and more for comprehensive immune defense.
Zazzee’s Extra Strength formula goes beyond basic vitamin C + zinc by adding six additional immune-supporting ingredients. The 180-capsule bottle provides a generous 3-month supply. Each serving delivers vitamin C and zinc as the foundation, enhanced by elderberry extract, echinacea, garlic, turmeric, oregano oil, and ginger for multi-pathway immune support.
Pros:
8 immune-supporting ingredients in one supplement
180 vegan capsules — full 3-month supply
Includes elderberry, echinacea, and turmeric
Cons:
Requires 2 capsules per serving
Individual ingredient doses are lower due to the 8-in-1 format
Best for: Those who want a comprehensive immune formula with vitamin C and zinc plus additional herbal support
3. Snap Supplements Men’s Multivitamin – Best Multivitamin with C & Zinc
Snap Supplements Men’s Multivitamins – Daily Vitamins & Minerals for Men – Vitamin D, B12, Zinc, Herbs & Vitamin C for Energy & Immune Support, Multivitamin for Men, 60 Capsules
Daily Multivitamin for Men – Complete blend of essential vitamins, minerals, and herbs to support overall men’s health and wellness.
Energy & Vitality Support – Contains Vitamin B12, Vitamin D, and Zinc to help promote natural energy, strength, and metabolism.
Immune System Support – With Vitamin C and key nutrients to encourage daily immune defense and resilience.
Comprehensive Men’s Formula – Designed to fill common nutrient gaps and support active, balanced lifestyles.
Convenient Daily Use – Each bottle includes 60 easy-to-take capsules, providing a one-month supply of daily men’s multivitamins.
Snap Supplements delivers vitamin C, zinc, and vitamin D3 alongside a full spectrum of daily vitamins and minerals for men who want immune support built into their multivitamin.
Rather than taking separate vitamin C and zinc supplements, this men’s multivitamin includes both at meaningful doses alongside over 15 other essential nutrients. The formula includes vitamin D3 for additional immune support, B vitamins for energy, and minerals for overall health. Each bottle provides a full 30-day supply of vegetarian capsules.
Pros:
Vitamin C + zinc built into a complete daily multivitamin
Added vitamin D3 for enhanced immune support
Consolidates multiple supplements into one
Cons:
Vitamin C and zinc doses may be lower than standalone products
Marketed for men, though the formula works for anyone
Best for: Men who want vitamin C and zinc immune support as part of a complete daily multivitamin
4. Sambucus Elderberry Gummies with Vitamin C & Zinc – Best Gummies
Sambucus Elderberry Gummies for Adults – Immune Support Supplement with Vitamin C and Zinc – Enhanced Formula for Daily Defense – 60 Count, 1 Month Supply, Berry Flavor – Convenient Wellness
Elderberry Immune Support – Our elderberry gummies are packed with Sambucus elderberry, a powerful antioxidant that helps support immune function for daily wellness.
Elderberry Vitamin C and Zinc – Each gummy combines elderberry with vitamin C and zinc, offering a triple-action blend to support immune defense and promote a healthy response to seasonal challenges.
Delicious Berry Flavor Immune Support Gummies – Enjoy the benefits of elderberry, vitamin C, and zinc in a tasty, elderberry gummy that makes supporting your immune system a delicious part of your daily routine.
Convenient Immune Gummies for Adults – These elderberry gummies are an easy and convenient way to support your immune health, perfect for those on-the-go or looking for a tasty alternative to capsules or tablets.
We Believe in High Standards – Our elderberry vitamins are produced in a GMP facility, ensuring rigorous testing for a supplement you can trust.
These elderberry gummies combine sambucus elderberry extract with vitamin C and zinc for a triple-action immune support gummy that tastes great.
Each serving delivers a meaningful dose of elderberry extract — rich in anthocyanins — alongside vitamin C and zinc. The gummy format makes daily immune support enjoyable, and the combination of all three ingredients provides multi-pathway defense. These are one of the best-selling immune gummies on Amazon for good reason.
Pros:
Triple combination of elderberry + vitamin C + zinc
Delicious gummy format for easy daily use
Well-reviewed with thousands of positive ratings
Cons:
Contains added sugar
Lower vitamin C and zinc doses than capsule alternatives
Best for: Anyone who wants a tasty gummy that combines elderberry with vitamin C and zinc for immune defense
5. Natures Craft Kids Immune Support Gummies – Best for Kids
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Natures Craft delivers vitamin C, zinc, and vitamin D in a vegan gummy designed specifically for children’s immune systems.
These kid-friendly gummies combine vitamin C and zinc at age-appropriate doses with vitamin D3 for comprehensive immune support. The vegan formula is free from artificial colors and flavors, and the gummy format makes it easy to get kids to take their daily immune vitamins without fuss. Each bottle provides a 30-day supply.
Pros:
Age-appropriate doses of vitamin C, zinc, and vitamin D
Vegan and free from artificial colors and flavors
Kids-friendly taste makes daily compliance easy
Cons:
Lower doses than adult formulas
Contains natural sugars
Best for: Parents looking for a clean, vegan immune gummy for their children
6. Elderberry Capsules with Zinc & Vitamin C – Best Capsule Combo
Elderberry Capsules with Zinc and Vitamin C for Adults – Immune Support Vitamins for Women and Men – Black Sambucus Elderberry Vitamin C and Zinc – Immune Defense Multiminerals Supplement, 60 Count
3 layers of natural immune support in 1 daily supplement: BioSchwartz elderberry capsules combine 500mg sambucus elderberry fruit (sambucus nigra) with 7mg zinc and 120mg vitamin C into a potent blend of beneficial vitamins, minerals, and herbal flower essences. This expertly crafted formula is designed to support a healthy immune system in men, women, and children
Rich in beneficial minerals and antioxidants: Because sambucus elderberry naturally has high levels of antioxidants and multiminerals, it’s been traditionally used for thousands of years to support a healthy immune system. Elderberry also plays a key role in a number of critical functions within the body and may help fight free-radicals while reducing oxidative-stress
Natural support for smoother skin: along with elderberry, both vitamin C and zinc can help promote firm and healthy looking skin; vitamin C protects the skin’s collagen and elastin, while zinc can help promote the formation of connective tissues, an important factor in maintaining skin health
Expert formulated: BioSchwartz sambucus elderberry capsules were expertly formulated with premium natural quality ingredients to promote immune support and a healthy immune system
2 month supply of daily immune support: Every bottle of Bioschwartz sambucus elderberry capsules comes filled with 60 1-per-day veggie capsules (a full 2 month supply), each one containing an exclusive blend of natural elderberry, zinc, and vitamin C
This capsule-based formula combines elderberry extract with vitamin C and zinc for those who want the immune benefits of all three without gummy sugars.
Each serving delivers elderberry extract alongside immune-supporting doses of vitamin C and zinc in an easy-to-swallow capsule format. The capsule form allows for higher doses of each ingredient compared to gummy alternatives, and eliminates the added sugars found in chewable versions. The formula is designed for year-round immune support.
Pros:
Higher doses per serving than gummy alternatives
No added sugars or artificial sweeteners
Triple immune formula in convenient capsules
Cons:
Capsules are less appealing for those who dislike pills
No added flavor — strictly functional
Best for: Adults who want a sugar-free, higher-dose vitamin C + zinc + elderberry combo in capsule form
7. BioSchwartz Elderberry Gummies with Zinc & Vitamin C – Best Premium Gummies
BioSchwartz Elderberry Gummies with Zinc and Vitamin C – Natural Immune Support for Adults & Kids – Black Sambucus Elderberries – Third-Party Tested, Non-GMO, Vegan Multimineral Supplement, 60 Count
Supports Your Immune System: These elderberry gummies are expertly formulated with Vitamin C and zinc to strengthen your body’s natural immune support defenses, offering essential nutrients that your body needs in tasty and easy-to-chew gummies
A Delightful Wellness Boost for Adults & Kids: Say goodbye to hard-to-swallow pills and embrace the convenience of elderberry gummies for adults and children that make immune support easy and enjoyable for everyone in the family
Premium Black Elderberry: Experience the multifaceted benefits of black sambucus elderberries, renowned for their antioxidant properties; these gummies support your body’s natural defenses while being kind to sensitive dietary needs with their non-GMO and vegan-friendly formulation
Convenient Whole Body Health Support: The compact 60-count bottle of sambucus immune gummy elderberry is your go-to for on-the-go wellness, ensuring you never miss out on an essential immunity boost wherever you are
The New Standard in Elderberry Supplements: BioSchwartz elderberry gummies are made in the USA with premium globally-sourced ingredients and third party tested for purity, potency and quality
BioSchwartz combines elderberry, vitamin C, and zinc in a premium gummy formula backed by the brand’s commitment to third-party testing and quality control.
BioSchwartz is known for high-quality supplements with transparent labeling and third-party verification. These elderberry gummies deliver a natural immune support blend with vitamin C and zinc at doses designed for daily use. The brand’s focus on quality control gives consumers extra confidence in purity and potency.
Pros:
Third-party tested for purity and potency
Reputable brand with strong quality standards
Pleasant-tasting gummy with natural flavors
Cons:
Premium pricing compared to similar products
Gummy format limits dosage compared to capsules
Best for: Those willing to pay a premium for a trusted, third-party tested immune gummy
8. WellPath Boost Elderberry Gummies with Zinc & Vitamin C – Best Budget Pick
WellPath Boost Elderberry Gummies with Zinc & Vitamin C | Immune Support Supplement for Adults | Immunity Booster Vitamins | Sambucol Black Gummy | Non-GMO & Vegan, 60 Ct
[Immune Support Gummies for the Family] We packed so many immune supporting benefits into these Elderberry immunity gummies that not only support your health but taste delicious and go down easy! Help keep you and your family healthy all year round!
[3-in-1 Trio: Vitamin C + Elderberry + Zinc Gummies] Boost combines Sambucus Black Elderberry with Zinc and Vitamin C for you to enjoy a powerful 3-in-1 immune booster for adults. Comes in convenient gummies to take at home or on the go.
[Seasonal Immune System Support] Boost elderberry herbal supplement gummies are rich in antioxidant vitamin C, which can help support resilience, especially during the winter season. Elderberry, Vitamin C, and Zinc provide amazing immune support!
[Delicious and Easy to Chew] No hard to swallow capsules or pill, no mess, no hassle – just tasty immunity gummies! Eat 2 Elderberry Gummies per day as your daily immunity supplement.
[Black Sambucus Elderberry Benefits] Black Elderberry is believed to have immune-boosting properties & may shorten cold/flu duration & reduce symptoms. It has been used for centuries as a powerful wellness and immunity booster.
WellPath Boost delivers elderberry, vitamin C, and zinc immune support at one of the most competitive price points in the category.
This gummy formula combines all three core immune-support ingredients — elderberry extract, vitamin C, and zinc — at a price that makes daily supplementation affordable for the whole family. The gummies have a pleasant berry flavor and deliver consistent doses per serving. WellPath focuses on accessible wellness without cutting corners on key ingredients.
Pros:
Competitive price point for a triple immune formula
Good-tasting berry flavor
Combines elderberry, vitamin C, and zinc in each serving
Cons:
Brand is less well-known than premium competitors
Contains added sugar like most gummy supplements
Best for: Budget-conscious shoppers who want a solid vitamin C, zinc, and elderberry gummy without paying premium prices
9. Clear Skin Supplement with Zinc – Best for Skin + Immune Support
Clear Skin Supplement with Zinc, DIM & Probiotics | 3-in-1 Balance, Glow & Health Skin Support | Triple Action Hyaluronic Acid, Niaciminide & Vitamins for Hormone, Complexion & Gut Support | 180 Ct
TRIPLE ACTION FOR SKIN BALANCE, GLOW & HEALTH: This Clear Skin Supplement is strategically formulated to support the 3 factors that influence your skin the most: hormone balance, the gut microbiome, and skin-essential nutrition.*
FEATURING DIM FOR BALANCE: Clear-3 is formulated with our #1 DIM supplement. DIM, or diindolylmethane, is a well-studied compound renowned for supporting hormone balance, and in turn, promoting balanced and healthy skin.*
WITH PROBIOTICS FOR GUT SUPPORT: Your gut microbiome is absolutely foundational to glowing, radiant skin. That’s why Clear-3 includes 18 billion CFU of Lactobacillus and Bifidobacterium probiotic strains, to support overall gut health and skin complexion.*
CLEAR SKIN VITAMINS WITH ZINC: Zinc is crucial in our formula, along with essential nutrients for clear, glowing, and healthy skin. Each serving supports hydration, collagen production, sebum control, and barrier function, with Hyaluronic Acid, Niacinamide, Selenium, Vitamin B6, and more.*
UNCOMPROMISING QUALITY: Clear-3 skin supplements for men and women by SMNutrition are manufactured in a facility that adheres to cGMP guidelines. They are Third-Party Tested, and every bottle contains 180 clear skin pills (a 90-day supply).
This supplement delivers zinc alongside DIM and probiotics for a formula that supports both immune function and clear skin health.
While primarily marketed for skin health, this 3-in-1 supplement provides a meaningful dose of zinc — a mineral critical for both immune cell function and skin repair. The addition of DIM (diindolylmethane) supports hormonal balance, while probiotics contribute to gut-immune axis health. It’s a smart choice for those who want zinc’s immune benefits alongside skin-clearing support.
Pros:
Dual-benefit formula for immune and skin health
Added probiotics for gut-immune support
DIM supports hormonal balance
Cons:
Not a traditional vitamin C + zinc formula
Lower vitamin C content than dedicated immune supplements
Best for: Those who want zinc-based immune support that also helps with skin clarity and hormonal balance
How to Choose the Best Vitamin C with Zinc Supplement
Look for vitamin C doses between 500mg and 1000mg per serving. Doses above 1000mg offer diminishing returns since the body can only absorb about 200mg at a time, though higher doses throughout the day can be beneficial during illness. Zinc doses between 15mg and 30mg per day are ideal for immune support — avoid exceeding 40mg daily unless directed by a healthcare provider, as excess zinc can cause copper deficiency.
Consider the form of each nutrient. Ascorbic acid is the most studied form of vitamin C and is effective for most people. Buffered vitamin C (sodium ascorbate or calcium ascorbate) is gentler on sensitive stomachs. For zinc, look for zinc picolinate, zinc gluconate, or zinc citrate — these forms are more bioavailable than zinc oxide.
Decide whether you want a dedicated vitamin C + zinc supplement or a combination product with additional immune ingredients like elderberry, echinacea, or vitamin D. Standalone formulas deliver higher doses, while combination products offer broader immune support at lower individual doses.
Check for third-party testing and GMP certification. Supplements aren’t regulated as tightly as pharmaceuticals, so independent verification helps ensure you’re getting what’s on the label. Brands that display USP, NSF, or third-party testing seals offer extra peace of mind.
Frequently Asked Questions
What do vitamin C and zinc do for the immune system?
Vitamin C supports the immune system by stimulating white blood cell production, acting as an antioxidant to protect immune cells from damage, and supporting the skin barrier — the body’s first line of defense. Zinc is essential for immune cell development, communication between immune cells, and the inflammatory response. Together, they support both innate and adaptive immunity.
How much vitamin C and zinc should I take daily?
For general immune maintenance, 500–1000mg of vitamin C and 15–30mg of zinc per day is a widely recommended range. During cold and flu season or at the first sign of illness, some people temporarily increase vitamin C intake to 1000–2000mg per day. Do not exceed 40mg of zinc daily for extended periods without medical guidance.
When is the best time to take vitamin C and zinc?
Vitamin C can be taken at any time of day and is well absorbed with or without food. Zinc is best taken with food to prevent stomach upset. If taking both in one supplement, taking it with a meal is the safest approach. Some people split their dose — taking vitamin C in the morning and zinc with dinner — for more consistent absorption.
Are there any side effects of vitamin C and zinc supplements?
High doses of vitamin C (above 2000mg per day) can cause digestive issues like diarrhea, nausea, and stomach cramps. Zinc at doses above 40mg per day can cause nausea, vomiting, and may interfere with copper absorption over time. Taking zinc on an empty stomach commonly causes nausea. At recommended doses, both nutrients are generally very well tolerated.
Can I take vitamin C and zinc together?
Yes, vitamin C and zinc are safe and effective to take together. In fact, many immune support supplements combine them specifically because they work through complementary mechanisms. Vitamin C can actually enhance zinc absorption when taken at the same time. There are no known negative interactions between the two nutrients.
How long does it take for vitamin C and zinc to support immunity?
Both nutrients begin working immediately at the cellular level, but noticeable benefits typically develop over 1–2 weeks of consistent daily use as tissue levels build up. Research shows that people who supplement regularly with vitamin C and zinc before getting sick tend to experience shorter symptom duration compared to starting supplementation after illness onset.