Saffron has emerged as one of the most clinically studied natural mood enhancers available. Multiple peer-reviewed studies show that saffron extract — particularly its active compounds crocin and safranal — can support healthy mood, reduce occasional stress, and promote emotional balance. These are the best saffron supplements for mood support available right now.
Quick Comparison
Product
Key Ingredient
Form
Best For
Rating
Effective Nutra Saffron Gummies
Saffron + Vitamin D2 + Passion Flower
Gummies
Overall Best
4.5/5
Luma Nutrition Saffron Extract
Saffron Extract 88.5mg
Capsules
Best Pure Saffron
4.4/5
Saffron Supplements Gummies 100mg
Saffron + Magnesium Glycinate + L-Theanine
Gummies
Best Mood Stack Gummy
4.3/5
Saffron Gummies for Kids & Adults
Saffron 88.5mg + Magnesium 300mg
Gummies
Best Family Option
4.3/5
NutraHarmony Saffron Extract
Saffron Extract 88.5mg
Capsules
Best 3-Month Supply
4.4/5
SOLARAY Saffron Extract (Affron)
Affron® Saffron Extract
VegCaps
Best Clinically Studied
4.5/5
Nutricost Saffron Extract
Saffron Extract 88.5mg
Capsules
Best Value
4.4/5
1. Effective Nutra Saffron Gummies – Best Overall
Effective Nutra Saffron Gummies | Sugar-Free Supplement with Vitamin D2, Passion Flower, St. John’s Wort & GABA | Positive Mood, Digestion, Energy | Natural Berry Flavor, Made in USA (90 Count)
#1 ULTIMATE SAFFRON GUMMY: Not a fan of swallowing large capsules? Our sugar free saffron gummies taste good & go down easy. 90 Gummies in a bottle for the best value out there!*
GET ALL THE BENEFITS: Our saffron supplement is packed with a 5-in-1 blend that may promote positive mood and attitude, digestion, physical fitness, increase in energy and focus, stress relief, heart health and brain function.*
SUPPORTS HEALTHY MOOD: Saffron extract has a long history of traditional use for supporting a healthy mood and promoting emotional balance. A great way to maintain a positive attitude and mood all day long!*
HEALTHY & DELICIOUS: Yes, we did it! At Effective Nutra we want to provide a healthy and enjoyable experience. Our saffron gummies are naturally berry flavored. With no artificial colors or flavors, you can be sure you’re getting the most nourishing health gummies out there!*
EFFECTIVE NUTRA’S SEAL OF EXCELLENCE: QUALITY YOU CAN TRUST: Our supplements are Vegan, Gluten-Free, Non-GMO, Third Party Tested, GMP Certified and proudly Made in USA with Globally Sourced Ingredients. That’s the Effective Nutra seal of excellence!*
A sugar-free saffron gummy that pairs saffron extract with vitamin D2 and passion flower for comprehensive mood support.
Effective Nutra combines saffron extract with vitamin D2 and passion flower in a sugar-free gummy format. Vitamin D deficiency is strongly linked to mood disorders, and passion flower has been used for centuries as a natural calming agent. This triple-action formula addresses mood from multiple pathways — serotonin support via saffron, vitamin D for neurological health, and passion flower for relaxation. The sugar-free formulation makes it suitable for those watching their sugar intake. Made in a GMP-certified facility.
Pros:
Triple-action mood formula: saffron + vitamin D2 + passion flower
Sugar-free gummy format
GMP-certified manufacturing
Cons:
Vitamin D2 is less bioavailable than D3
Gummy format may have lower saffron dose than capsules
Best for: Anyone who wants a comprehensive mood support gummy with saffron as the lead ingredient
2. Luma Nutrition Saffron Extract Capsules – Best Pure Saffron
Luma Nutrition Saffron Extract Capsules – Premium Saffron Supplements – 88.50 mg Pure Saffron Pills – Mood Support – Eye Support – Made in The USA – 60 Capsules
Potent & Effective – Elevate Health Naturally: Unleash the power of our natural saffron extract, a top-tier supplement for improved macular eye health, mood enhancer, brain support and energy support. Elevate your wellness journey with proven efficacy.
Many Health Benefits: Our optimized saffron powder is used by many as an effective eye supplement for both men and women. It may also help support overall metabolic function for healthy weight management.
Mood Boosting Marvel – Elevate Positivity: Transform your mood with Luma Nutrition saffron pills, a renowned mood support supplement. Embrace a natural mood boosting that promotes serotonin and positive energy support without the added sugar of Saffron gummies.
Easy 1-Month Supply: Create a solid daily routine with Luma’s 30-day supply of premium saffron supplements for kids and adults. Makes the perfect monthly subscription! Always stay in stock and save money at the same time!
USA-Made Excellence – Veteran Owned: Trust Luma Nutrition’s saffron capsules, crafted in GMP certified US facilities. We’re family-owned, committed to quality, and here to support your well-being journey.
A straightforward 88.5mg saffron extract capsule from a reputable supplement brand focused on purity.
Luma Nutrition delivers 88.5mg of pure saffron extract per capsule — the dose most commonly used in clinical studies on mood. There are no fillers, blends, or unnecessary additives cluttering the formula. This is a clean, focused saffron supplement for people who want the mood benefits of saffron without anything extra. The 88.5mg dose aligns with the dosage range shown in research to support healthy mood and emotional well-being.
Pros:
Clinically studied 88.5mg dose
Clean, focused formula — saffron extract only
Reputable brand with strong customer reviews
Cons:
Capsule format — not ideal for those who prefer gummies
No additional mood-supporting ingredients
Best for: Purists who want a clinically dosed saffron supplement without any extras
3. Saffron Supplements Gummies 100mg with Magnesium & L-Theanine – Best Mood Stack
Saffron Supplements Gummies 100mg – 100% Pure Saffron Extract with Magnesium Glycinate, L-Theanine, Turmeric, Ashwagandha, Honey & Vitamin B Complex for Mood & Power, Antioxidant, Vitality – 60 Count
Organic Saffron Extract for Maximum Purity & Potency >>> Our saffron supplements each serving delivers 100mg of 0.3% Safranal extract from 100% certified organic saffron silk grown in Spain. Unlike many brands that use blends, or lower-grade saffron, we use only authentic Spanish saffron for reliable results. Specially designed for those seeking natural mood balance, focus, energy well-being.
Mood & Energy Support >>> Known as the “happy spice,” saffron has long been celebrated for its uplifting effects and ability to brighten the brain. Each saffron gummy paired with a synergistic blend of magnesium glycinate, ashwagandha, L-theanine & rhodiola rosea. This unique formula works to calm mood, keep natural energy & brain clarity—caffeine free. Whether you’re powering through a busy day or simply want a gentle lift in mood energy, our saffron offers a delicious way to feel your best.
LESS OF HUNGER, CLOSER TO GOALS >>> Surprisingly, saffron can support healthy eating habits, help keep your body healthy, provide energy support, making it more efficiently as the management gummies to help you eat healthy portions, reduce mood snacking frequency due to temporary bad mood, and consume less calories. In addition enriched with Vitamin C, D3, Folate, Vitamin B6, and Vitamin B12, they also help maintain immune strength and natural energy—keeping you balanced and motivated every day.
HEALTHY LIFESTYLE ON THE GO >>> Enjoy the power of saffron every day—without the hassle of capsules, pills, teas, or powders. Our convenient formula makes it easy to get your daily dose, wherever life takes you. Packed with the antioxidant-rich benefits of Saffron & Turmeric, our supplement helps support your overall wellness, including mood balance, eye health, antioxidant support and cellular protection. Take 1 gummy a day help keep you feeling and seeing your best.
UNMATCHED QUALITY & SUPPORT >>> Our gummies infused with Manuka Honey for added wellness, these gummies are a tasty, on-the-go alternative. All of our whole herb saffron extract gummies are manufactured, tested, and bottled in a 3rd-party tested facility for superior quality and consistency. Please contact us if you have any questions, we offer “always online” support and will take care of you.
A saffron gummy enhanced with magnesium glycinate and L-theanine for a complete mood and relaxation stack.
This formula pairs 100mg of pure saffron extract with magnesium glycinate and L-theanine — two ingredients with strong evidence for promoting calm and reducing anxiety. Magnesium glycinate is the most bioavailable and gentle form of magnesium, and L-theanine (found naturally in green tea) promotes alpha brain waves associated with relaxed alertness. Together, these three ingredients create a well-rounded mood support gummy that addresses both emotional balance and physical relaxation.
Pros:
Combines saffron with magnesium glycinate and L-theanine
100mg saffron — above the standard 88.5mg clinical dose
Addresses both mood and relaxation
Cons:
Magnesium dose in gummy form may be modest
Multiple active ingredients mean smaller individual doses
Best for: Those who want a complete mood and calm stack in a single gummy supplement
4. Saffron Gummies for Kids & Adults with Magnesium Glycinate – Best Family Option
Sale
Saffron Gummies for Kids&Adults with Saffron 88.5mg + Magnesium Glycinate 300mg | Max Strength Saffron Supplements with St. John’s Wort, L-Theanine, Rhodiola , Rosemary – Supports Mood & Focus
Ultra-High Content–Our saffron supplements leverage cutting-edge herbal extraction technology. Each serving saffron gummy delivers 88.5 mg of premium saffron extract, standardized to 0.5% Safranal. This high-quality saffron extract in our saffron supplements is chosen to provide noticeable mood and cognitive benefits.
Proprietary Mental Clarity & Calm Blend– Our saffron gummies supplement include an exclusive mix of St. John’s Wort, L-Theanine, Rhodiola, Rosemary, and Passion Flower extracts. This potent blend in our saffron supplements is formulated to foster mental clarity and relaxation, helping you navigate daily challenges with ease.
Superior Absorption and Bioavailability–Our saffron extract gummies are made using cutting-edge 10:1 extraction technology for rapid absorption and efficacy. The premium formula is designed for relaxation and a calm mood.Perfect for maintaining a positive outlook and sharp focus throughout your busy day.
Powerful Antioxidant Support–Each serving saffron gummy is packed with 300mg of highly bioavailable Magnesium Glycinate. Saffron extract and magnesium glycinate are crafted for relaxation and restful sleep. Additionally, our saffron supplements include essential vitamins B6, B12, D3, and Zinc to aid in melatonin synthesis, offering a melatonin-free option for regulating circadian rhythm, ensuring restful sleep and refreshed mornings without grogginess.
Premium, Trusted Quality & Purity– We are committed to pure and effective ingredients. Non-GMO, gluten-free, and gelatin-free. Produced in a GMP-certified facility, every batch is crafted to meet our high standards for quality and safety. Each bottle contains a convenient 30-day supply.
A saffron and magnesium gummy suitable for both kids and adults, delivering 88.5mg saffron and 300mg magnesium glycinate.
This family-friendly formula delivers 88.5mg of saffron extract alongside 300mg of magnesium glycinate per serving. The combination supports mood, focus, and relaxation for both children and adults. Magnesium glycinate is well-tolerated and doesn’t cause the digestive issues associated with other magnesium forms. The gummy format makes compliance easy for kids who resist capsules or tablets. A solid choice for households where multiple family members want mood support from the same product.
Pros:
Suitable for both kids and adults
300mg magnesium glycinate — meaningful dose
Clinically studied saffron dosage
Cons:
Kids may need reduced serving size — check label guidance
Gummies contain some added sugar
Best for: Families looking for a single mood support supplement that works for all ages
5. NutraHarmony Natural Saffron Extract 88.5mg – Best 3-Month Supply
Sale
Natural Saffron Supplements – Pure Saffron Extract 88.5 mg – Made in USA – Mood | Focus | Vision | Energy Support – Eye Health for Women & Men – NonGMO Vegan Pills – 90 Powder Capsules, 3 Month Supply
𝐅𝐨𝐜𝐮𝐬, 𝐌𝐨𝐨𝐝 & 𝐕𝐢𝐬𝐢𝐨𝐧 – A great compliment to your A+ study or working day! Saffron supplements may support focus, learning, concentration, and good mood! It supports the structure and function of the retina and lens cells in people of age and maintains eye health as well.
𝐏𝐮𝐫𝐞 𝐒𝐚𝐟𝐟𝐫𝐨𝐧 𝐄𝐱𝐭𝐫𝐚𝐜𝐭 – Sunshine spice blend for your wellness. It is rich in antioxidants, supports memory, energy with learning ability & brighter mood. What can be better than a power in a single capsule?
𝟖𝟖.𝟓 𝐦𝐠 𝐒𝐚𝐟𝐟𝐫𝐨𝐧 𝐂𝐚𝐩𝐬𝐮𝐥𝐞𝐬 – Good vibes only! The optimal dosage for every day for men and women! Three months’ supply for a perfect lifestyle & health. Saffron supplements are perfect for maintaining energy levels and a positive outlook throughout the whole day!
𝐔𝐒𝐀-𝐦𝐚𝐝𝐞 – Saffron from NUTRAHARMONY does not contain GMOs; it’s dairy-free, gluten-free, nut-free, wheat-free, soy-free, nightshade-free, and sugar-free. Also, it’s a perfect addition to your gluten-free & vegan lifestyle with mood & mind support and significant effects.
𝐖𝐞 𝐯𝐚𝐥𝐮𝐞 𝐲𝐨𝐮𝐫 𝐞𝐱𝐩𝐞𝐫𝐢𝐞𝐧𝐜𝐞 – NUTRAHARMONY pure Saffron Capsules are an excellent and effortless choice for improving your health. If you want to share your experience or have questions, message us. Our support team works 24/7. Maintain your health anytime, anywhere with a saffron extract supplement!
A 90-capsule bottle providing a full three months of clinically dosed saffron extract for sustained mood support.
NutraHarmony delivers 88.5mg of pure saffron extract per capsule in a 90-count bottle — one of the best value propositions in the saffron supplement market. The formula is free from GMOs, dairy, gluten, soy, and artificial additives. Made in the USA and third-party tested for purity and potency. The three-month supply makes this a practical choice for anyone committed to long-term mood support, as saffron’s benefits are most pronounced with consistent daily use over 4-8 weeks.
Pros:
90 capsules — full 3-month supply
Clinically studied 88.5mg dose
Third-party tested, USA made
Cons:
Capsule only — no gummy option available
Single-ingredient formula
Best for: Anyone looking for a long-term, cost-effective saffron supplement for daily mood support
6. SOLARAY Saffron Extract (Affron®) – Best Clinically Studied
Sale
SOLARAY Saffron Extract – Sleep and Positive Mood Support – Vegan and Gluten Free Saffron Supplements – Lab Verified – 60-Day Guarantee – 30 Servings, 30 VegCaps
Mood Support Supplement – Made with clinically studied Affron (R) Saffron, a saffron extract that uses a proprietary process to ensure the highest quality, our Vital Extracts Saffron supplement is designed to help support a positive mood.*
Sweet Dreams – With powerful plant compounds, Saffron extract may help provide many health benefits including sleep support to help you start each day feeling revitalized.*
Powerfully Potent – Every 1-VegCap serving size is standardized to contain 1 mg or 3.5% Lepticrosalides (R), a key compound of saffron believed to be responsible for its beneficial properties.
Making a Difference – To reduce our carbon footprint, Solaray bottles are made from post-consumer recycled resin, helping keep plastic out of our landfills and oceans; we’ve also installed solar panels as an additional energy source at our Ogden, Utah facility—to power the processes and products that help you Live Brighter.
Trusted Brand – Vegan, gluten free, made in our GMP-certified facility, and always tested in our own state-of-the-art lab in Utah to bring you the best possible quality.
Uses patented Affron® saffron extract — the most clinically studied form of saffron for mood and sleep support.
SOLARAY uses Affron®, a patented saffron extract standardized to contain 3.5% Lepticrosalides® — the bioactive compounds believed to be responsible for saffron’s mood-enhancing effects. Affron® is the most clinically researched form of saffron available, with multiple peer-reviewed studies supporting its effectiveness for positive mood and sleep quality. Each VegCap delivers the standardized dose in a vegan, gluten-free format. SOLARAY manufactures in a GMP-certified facility in Utah and tests in their own state-of-the-art lab.
Pros:
Patented Affron® — the gold standard for clinically studied saffron
Standardized to 3.5% Lepticrosalides® for guaranteed potency
Lab-verified by SOLARAY’s own testing facility
Cons:
Only 30 servings per bottle
Premium price for the patented ingredient
Best for: Those who want the most scientifically validated saffron extract available
7. Ultra6 Saffron Supplements – Best for Mood & Eye Health
Ultra6 Saffron Supplements – 100% Pure Saffron Extract Capsules and Mood Enhancer for Women and Men – Natural Supplement for Eye Health (90 Servings)
BOOST YOUR MOOD: Feeling down? Our saffron extract capsules are here to lift your spirits. These saffron supplements boost mood and energy naturally, offering daily positivity and calm. Ideal for promoting a happier, balanced life.
SUPPORT YOUR EYES: Keep your eyes healthy with our saffron supplement. They help maintain clear vision and protect against eye strain, supporting better eye health and clarity, whether you’re spending long hours in front of screens or just want to keep your eyes sharp.
BETTER DIGESTION: Experience smooth digestion with our mood support supplement. These capsules reduce bloating, cramping, and constipation for a healthier digestive system. Enjoy improved digestion and fewer issues with regular use.
MADE IN THE USA: Trust the quality of our saffron capsules, made in a GMP-certified USA facility. Non-GMO and vegan, they ensure purity and safety in every capsule. Enjoy a premium, effective, and ethically produced energy support supplement.
CLEAN AND PURE: They’re 100% vegan and non-GMO, providing a natural and wholesome health option. Free from artificial additives and animal products, our capsules offer a clean, responsible choice for your wellness. Feel good about taking a clean, pure saffron supplement!
A dual-purpose saffron capsule delivering 88.5mg for both mood enhancement and eye health support.
Ultra6 (by ZuvaLabs) delivers 88.5mg of saffron extract in a straightforward capsule designed to support mood, focus, and eye health simultaneously. Saffron’s high carotenoid content — particularly crocin — supports both brain function and retinal health. The 90-capsule bottle provides a full three months of daily supplementation. The formula is pure, with no unnecessary fillers or blends, letting the saffron extract do the heavy lifting.
Pros:
Dual-purpose: mood and eye health support
90 capsules — 3-month supply
Clean formula without unnecessary additives
Cons:
No additional mood-supporting ingredients like magnesium or L-theanine
Capsule form only
Best for: Adults who want saffron’s mood benefits along with eye health support in one supplement
8. Vimerson Health Pure Saffron Extract – Best for Mood & Appetite
Pure Saffron Supplements for Women & Men w/ 88.5mg Saffron Extract – Mood Support Supplement Plus Eye Health – Azafran Safron Spice Alternative to Gummies or Powder – 60 Vegan Count – 2 Month Supply
HIGH-POTENCY SAFFRON – Each serving delivers 88.5 mg of pure Saffron Extract, derived from Saffron Threads, with no blends or fillers. Our single-ingredient formula is designed to support overall well-being.*
MOOD & CALM SUPPORT – Premium Saffron Supplements help promote a balanced mood and support healthy dopamine levels. This natural approach helps you feel emotionally supported and resilient during times of stress.*
APPETITE & METABOLISM – This Safran supplement (Azafran) promotes appetite control and encourages mindful eating habits. May also aid normal metabolic function to complement a healthy lifestyle.*
VISION SUPPORT – Rich in powerful Carotenoids like Crocin and Safranal, our Safron helps maintain healthy eye function and supports long-term retinal health, making it a smart choice for vision wellness.*
HOW TO USE – Take 1 capsule daily, with or without food. For best results, use regularly. Some may notice results within 30–60 days of consistent use.
A cGMP and NSF-certified saffron capsule that supports mood, appetite balance, and eye health.
Vimerson Health delivers a premium saffron extract in a one-capsule-per-day format. The formula is designed to support healthy dopamine levels, promote emotional balance, and encourage mindful eating habits — saffron has been studied for its ability to reduce emotional eating and cravings. Made in a cGMP and NSF-certified facility in the USA with globally sourced ingredients. The 60-capsule bottle provides a full two months of daily use, and the brand has strong customer trust backed by rigorous quality testing.
Pros:
NSF and cGMP certified — top-tier quality assurance
Supports mood and healthy appetite simultaneously
Just one capsule per day
Cons:
Saffron dosage not prominently listed (may be lower than 88.5mg)
Premium pricing
Best for: Those who want mood support plus appetite management from a quality-certified brand
9. Nutricost Saffron Extract 88.5mg – Best Budget Option
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An 8-month supply of 88.5mg saffron extract capsules at one of the lowest costs per serving on the market.
Nutricost is known for delivering no-nonsense supplements at aggressive price points, and their saffron extract is no exception. The 240-capsule bottle provides up to 8 months of daily supplementation at 88.5mg per capsule. The formula is non-GMO, gluten-free, and manufactured in a GMP-compliant facility. For anyone who has already decided saffron works for their mood and wants to stock up affordably, Nutricost delivers unbeatable value per serving.
Pros:
240 capsules — up to 8 months of supply
Lowest cost per serving among quality saffron supplements
Clinically standard 88.5mg dose
Cons:
Basic packaging and branding
No additional mood-enhancing ingredients
Best for: Budget-conscious buyers who want a long-term supply of pure saffron extract
10. Pink Stork Hormone Balance Multivitamin with Saffron – Best for Women’s Mood
Pink Stork Hormone Balance Multivitamin for Women | 18-in-1 Vitex, Saffron, Ashwagandha, Magnesium | Mood, Energy, Cortisol, Adrenal Support | PMS, Perimenopause Support | 60 Vegan Capsules
18-in-1 Formula for Comprehensive Hormonal Support: Designed to support hormone harmony for women at every stage, this daily multivitamin delivers 100% DV of Vitamin B6, B12, and Iron, plus 825 mg of Vitex and Ashwagandha. Take 2 capsules daily, best with food.
Mood, Stress, + Adrenal Support: Magnesium and Ashwagandha work together to help maintain calm energy. Includes a light berry-scented insert so your supplements smell as good as they make you feel.
All-in-One Multivitamin + Herbal Hormone Formula: Delivers Iron, Vitamin D3, and B Vitamins for cognitive function and immune health. Replaces multiple bottles with two easy-to-swallow capsules.
Monthly PMS + Period Support: Hormone harmony for women to ease bloating and irritability. Helps to balance estrogen and other key hormones for cycle regularity.
Perimenopause + Hormone Transition Support: Supports perimenopause fluctuations with Dong Quai and Black Cohosh. Helps with hot flashes and mood stability.
An 18-in-1 women’s multivitamin featuring saffron alongside vitex, ashwagandha, and magnesium for hormone-related mood support.
Pink Stork takes a different approach by incorporating saffron into a comprehensive women’s hormone balance formula. The 18-in-1 blend includes vitex (chasteberry), ashwagandha, magnesium, and other nutrients that address the hormonal factors behind mood fluctuations. This is particularly relevant for women dealing with PMS, perimenopause, or cycle-related mood changes where hormone imbalance is the root cause. The saffron component adds proven mood support to an already robust formula.
Pros:
Addresses hormone-driven mood issues specifically
18-in-1 formula reduces the need for multiple supplements
Includes ashwagandha and vitex for hormonal balance
Cons:
Saffron dose may be lower within a multi-ingredient formula
Designed specifically for women — not a unisex option
Best for: Women experiencing mood changes related to hormonal fluctuations
How to Choose the Best Saffron Supplement for Mood
The clinically studied dose for saffron’s mood benefits is 88.5mg per day of saffron extract. Look for supplements that deliver this amount per serving. Some premium products use patented extracts like Affron®, which is standardized for specific bioactive compounds (Lepticrosalides®) and has the most robust clinical evidence behind it.
Saffron supplements come in capsules, gummies, and liquid drops. Capsules generally provide higher and more precise doses, while gummies offer convenience and taste at the cost of slightly lower potency. Choose based on your compliance preference — the best supplement is the one you’ll actually take consistently.
Check for third-party testing and GMP certification. Saffron is one of the world’s most expensive spices, which means adulteration is common in lower-quality supplements. Independent testing helps verify that you’re getting genuine saffron extract rather than fillers or substitutes.
Consider whether you want a standalone saffron supplement or a combination formula. Pure saffron capsules give you the most control over dosage, while combination products with magnesium, L-theanine, or vitamin D can address mood from multiple angles in fewer pills.
Frequently Asked Questions
What is saffron and how does it support mood?
Saffron is a spice derived from the Crocus sativus flower. Its active compounds — crocin and safranal — have been shown in clinical studies to support healthy serotonin levels in the brain. Multiple randomized controlled trials have found that saffron extract at 88.5mg daily can promote positive mood and emotional well-being comparable to some conventional options.
How much saffron should I take daily for mood support?
The most commonly studied dose is 88.5mg of saffron extract per day, typically split into one or two servings. Some products offer up to 100mg per serving. Doses above 200mg per day are not recommended and may cause side effects. Stick to the clinically studied range for the best balance of effectiveness and safety.
When is the best time to take saffron supplements?
Saffron can be taken at any time of day, with or without food. Some people prefer taking it in the morning to support a positive outlook throughout the day, while others take it in the evening — especially if using a formula that also supports sleep (like those with Affron®). Consistency matters more than timing.
Are there any side effects of saffron supplements?
At standard doses (88.5mg-100mg/day), saffron is generally well tolerated. Mild side effects can include dry mouth, drowsiness, or digestive discomfort. High doses above 200mg/day may cause more significant effects. Saffron should not be taken during pregnancy in supplemental doses, as it may stimulate uterine contractions. Always consult a healthcare provider if you’re taking medications, particularly antidepressants.
Can I take saffron with other mood supplements?
Saffron can generally be combined with other mood-supporting supplements like magnesium, L-theanine, and vitamin D. However, use caution when combining saffron with other serotonin-affecting substances, including St. John’s Wort, 5-HTP, or prescription antidepressants (SSRIs/SNRIs), as this could theoretically increase serotonin to uncomfortable levels. Consult a healthcare provider before stacking saffron with other mood-altering supplements or medications.
How long does it take for saffron to improve mood?
Most clinical studies show noticeable mood improvements within 4-8 weeks of daily saffron supplementation. Some users report feeling benefits within the first 1-2 weeks, but the full effects typically develop over a month or more of consistent use. Saffron works best as a long-term daily supplement rather than an as-needed remedy.